
Research that changes lives
The American Foundation for Addiction Research (AFAR) advances rigorous, independent research to improve the understanding and treatment of compulsive sexual behavior and betrayal trauma.
By supporting innovative scientific studies, we help build the evidence that leads to better diagnosis, more effective treatment, reduced stigma, and greater hope for individuals, couples, and families.
The research highlighted below reflects our commitment to advancing knowledge and improving recovery through science.
Advancing the Science of Compulsive Sexual Behavior

The American Foundation for Addiction Research (AFAR) is committed to advancing rigorous scientific research that improves understanding, diagnosis, and treatment of compulsive sexual behavior and related disorders.
One of our most significant initiatives has been our support of Dr. Patrick Carnes’ groundbreaking genetic research conducted through his Fulbright Canada-Palix Foundation appointment as Distinguished Visiting Chair in Brain Science at the University of Alberta.
This landmark study represents one of the largest and most comprehensive investigations ever undertaken in the field. More than 1,000 participants from research centers across the United States and Canada contributed genetic and clinical data, creating an unprecedented dataset for understanding the biological foundations of compulsive sexual behavior.
A Foundation for Future Discovery
The genomic sequencing phase of the study has now been completed, and researchers are actively analyzing the data. Scientific publications based on this unique dataset are currently in development and will continue to expand our understanding of the condition in the years ahead.
Researchers are examining important questions, including:
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What genetic factors are associated with compulsive sexual behavior?
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How do these genetic patterns compare with those found in substance use disorders and other behavioral addictions?
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Are there biological differences associated with distinct patterns of compulsive sexual behavior?
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How do genetics, brain function, and co-occurring psychological conditions interact to influence risk, severity, and treatment outcomes?
Why This Research Matters
Scientific evidence is essential to improving care.
This research has the potential to:
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Deepen our understanding of the neurobiology and genetics of compulsive sexual behavior.
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Inform more accurate diagnosis and personalized treatment approaches.
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Reduce stigma by strengthening the scientific understanding of addiction.
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Support broader recognition of compulsive sexual behavior within healthcare systems.
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Lay the groundwork for future discoveries that improve recovery outcomes.
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Building the Future of Research
The completion of genomic sequencing marks an important milestone, not the end of the journey. As findings are published and new questions emerge, AFAR remains committed to supporting high-quality, independent research that advances evidence-based treatment and gives hope to individuals, couples, families, and clinicians.
Together, we are building the scientific foundation for better understanding, better treatment, and better recovery.
